Our goal is to provide genetic testing for eyecare professionals as simply as possible. We also want to make it easy to explain the AvaGen test to your patients.
Avellino offers materials and other resources to help support your practice. Review these materials prior to testing and post-test.
If you are an eyecare patient, we invite you to visit our patient section
AvaGen Genetic Test Brochure
Educational support for eyecare health professionals and their staff.
Instructions for use brochure
Step-by-step instructions for administering and shipping the AvaGen test.
Patient Communication Tools
AvaGen Patient Brochure
Includes test benefits, methodology, administration steps, and more.
Long, medium, and short form web copy to include on your practice website.
AvaGen Test Requisition Form (TRF)
AvaGen Sample Report
Positive for Corneal Dystrophies
AvaGen Sample Report
Listen to experts share their views on genetics in ophthalmology, genetics for diagnosis, and more.
White Papers and Clinical Papers
TGFBI Corneal Dystrophy
Evaluation of TGFBI corneal dystrophy and molecular diagnostic testing.
Chao-Shern C, DeDionisio LA, Jang JH, et al..
Prevalence of transforming growth factor ß–induced gene corneal dystrophies in Chinese refractive surgery candidates.
Song Y, Sun M, Wang N, et al.
Prevalence of granular corneal dystrophy Type 2 (Avellino Corneal Dystrophy) in the Korean Population.
Lee JH, Cristol SM, Kim WC.
TGFBI Corneal Dystrophy-Post Refractive
Exacerbation of Avellino Corneal Dystrophy After LASIK in North America.
Banning C, Kim WC, Randleman B, et al.
Excimer laser exacerbation of Avellino corneal dystrophy.
Lee WB, Himmel KS, Hamilton SM, et al.
Recurrence of Corneal Dystrophy Resulting from an R124H Big-h3 Mutation After Phototherapeutic Keratectomy.
Inoue T, Watanabe H, Yamamoto S, et al.
A Clinical and Histopathologic Examination of Accelerated TGFBI Deposition After LASIK in Combined Granular-Lattice Corneal Dystrophy.
Aldave A, Sonmez B, Forstot L, et al.
Trauma-induced exacerbation of epithelial stromal TGFBI lattice corneal dystrophy.
Nithianandan H, Chao-Shern C, DeDionsio L.
Post-LASIK exacerbation of granular corneal dystrophy type 2 in members of a Chinese family.
Chao-Shern C, Me R, DeDionisio LA.
Avellino Corneal Dystrophy after LASIK.
Jun RM, Tchah H, Kim Tl, et al
Avellino Corneal Dystrophy Worsening after Laser In Situ Keratomileusis: Further Clinicopathologic Observations and Proposed Pathogenesis.
Awwad ST, Di Pascuale MA, Hogan RN, et al.
Sands of Sahara after LASIK in Avellino Corneal Dystrophy.
Flavio Mantelli, Alessandro Lambiase, Antonio Di Zazzo, and Stefano Bonini.
Slit-lamp examination shows multiple bilateral (right eye; left eye) crumb-like and lattice-like opacities of the stroma and multiple foci of fine granular infiltrates at the surgical flap interface.
Familial Case of Keratoconus with Corneal Granular Dystrophy in a Family of Iranian Origin.
Jadidi K, Aliasghar MS, and Morovvati S
Typical granular deposits and corneal topographies are observed in the corneas of the right (A) and left (B) eyes of Case 2 (father).
Association of Keratoconus with Granular Corneal Dystrophy.
Rasik B Vajpayee, MB BS, MS Grant R Snibson, FRACO Hugh R Taylor, MD, FRACO
Figure 1. Slit-lamp photograph of the left eye showing granular corneal opacities.
Figure 2. Corneal topography of the left eye showing marked inferior steepening.
Prevalence of keratoconus in pediatric patients in Riyadh, Saudi Arabia.
Torres-Netto EA, Al-Otabi WM, Hafezi NL
Age-specific Incidence and Prevalence of Keratoconus: A Nationwide Registration Study.
Godefrooj DA, de Wit GA, Uiterwaal CS, et al.
Insights into keratoconus from a genetic perspective
Burdon KP, Vincent AL.
5 prevalent TGFBI mutations and associated corneal dystrophy and codon change
Towards personalized allele specific CRISPR gene editing to treat autosomal dominant disorders
Christie K, Courtney D, DeDionsio L, et al.
Gene editing in the context of an increasingly complex genome
Blighe K, DeDionsio L, Christie KA, et al.
Advanced Sequencing Technologies: Methods and Goals.
Recommendations of the American Academy of Ophthalmology Task Force on Genetic Testing.
Stone EM, Aldave AJ, Drack AV, et al.